And it seems that the Pennsylvania-born politician can now impart everything he learned about how to make a great relationship work if he decides to become a full time wedding celebrant.
In the second wedding he officiated this weekend, Biden presided over the vows of Democratic National Committee staffer Henry Munoz and his new husband Kyle Ferrari on Saturday.
The former US VP wasn't the only star present however, actress Melanie Griffith was also front and centre at the nuptials of her pals, and made sure to get a few cute snaps for Instagram.
"My dearest friends Henry Munoz and Kyle Ferrari were married today by VP Joe Biden," the Working Girl actress captioned the pic, "Wishing them everlasting love and a joyous life journey!!"
It's not the first weekend the politician has spent overseeing the nuptials of staffers, in August last year Biden officiated the wedding of longtime White House staffers Joe Mahshie and Brian Mosteller, having got a special temporary certification from the District of Columbia to make it legal.
The politician publicly backed gay marriage in 2012 in the run-up to President Barack Obama's re-election.