The Modern Family star and Magic Mike Hunk exchanged vows in front of 400 family and friends at luxury resort The Breakers in West Palm Beach.
Sofia was walked down the aisle by Manolo, her 23-year-old son from her first marriage to teenage sweetheart Joe Gonzalez, who she divorced from in 1993 after just two years as husband and wife.
The Colombian beauty reportedly wore a custom wedding gown by one of her favourite red carpet designers, Zuhair Murad, while Joe sported a a John Varvatos tuxedo for the ceremony, and in lieu of gifts, the couple asked guests to donate to one of two charities, the St. Jude's Children's Hospital and Pittsburgh Children's Hospital.
Among the stars to witness the couple's nuptials were Sofia's Modern Family co-stars including Julie Bowen, Jesse Tyler Ferguson, Ed O'Neill, Eric Stonestreet, Sarah Hyland, Ty Burrell and Ariel Winter.
Other guests included Channing Tatum and wife Jenna Dewan Tatum, Reese Witherspoon, Matt Bomer, Paul Reubens, Anna Paquin and Stephen Moyer, Arnold Schwarzenegger, Hollywood mogul Harvey Weinstein, and fashion designer Georgina Chapman.
According to Entertainment Tonight, guests were asked to check their cell phones and cameras at the door before entering the wedding ceremony, but for the pre-wedding celebration on Saturday, there was no shortage of photographs and videos shared on social media.
Sofia, Joe, and their guests took to Instagram and Twitter to post their favourite moments from the cocktail and dessert party, which featured a performance by Colombian singer Jorge Celedon, and the former True Blood actor even got up on stage to serenade his bride-to-be with a rendition of Guns N' Roses classic Sweet Child O' Mine.
The newlyweds became engaged after a whirlwind romance in December during a romantic vacation in Hawaii.